Some states have significantly cut back on exemptions that aren't for valid medical reasons and home schooling isn't really a viable option for many people.
In addition, although I don't know if the case would stand up today, the Supreme Court has held that states can require vaccinations generally. (A 1905 case involving Massachusetts and smallpox vaccination.)
In addition, although I don't know if the case would stand up today, the Supreme Court has held that states can require vaccinations generally. (A 1905 case involving Massachusetts and smallpox vaccination.)