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by themgt 5479 days ago
If psilocybin was unknown and a pharmaceutical company discovered it along with the "appropriate" dose and published this study, their stock would be worth approximately the entire western world's GDP tomorrow

Except... it wouldn't because these people only required 4 doses, each a month apart, and then had better results 14 months later than every "take daily for life" psych drug on the market today

3 comments

It's not that easy :) The "take daily for life" pills work always; you can have the crappiest day of life and take a pill and you're happy. That's why they're addictive, even stuff like cigarettes or alcohol -- always work, always calm you down, bad trip impossible.

Psychedelics require preparation, and active cooperation on the patients side. If you think you can be depressed and suicidal and eat a mushroom and have it all gone you are in for a world of bad trip, that will have consequences after the bad trip: insanity, panic attacks, anxiety, and symptoms of PTSD. Basically, psychedelics aren't an immediate fix, they require preparation before and taking actions after the trip.

Psychonautics requires learning; experienced and knowledgeable people can guide their mind to benefit greatly from a bad trip, but most people are not be able to handle it, and delve even deeper into depression or whatever. Some killed themselves afterwards or during. Some have peed their pants while crying and shaking throughout the trip but came out better. Some had absolutely wonderful experiences with psychedelics.

From personal experience, your set and setting will determine whether you discover the wonders of the universe or hallucinate a penis staring at your face, thinking you are being raped for 8 hours. I am not joking.

People like immediate fixes, hence why psychedelic therapy doesn't get much attention.

> "take daily for life" pills work always

Sadly, the immediate fixes are not as sure fire as they are made to sound. Most people I've known on medications for depression and anxiety are juggling prescriptions and dosages to retain the benefits of the drugs. While SSRIs may not give you a "bad trip", they can have paradoxical effects as well as a host of terrible side effects, and withdrawal can be long and difficult. Benzodiazepenes are still widely prescribed and tolerance and addiction build rapidly in most people. For many people these work great but for many they do not, or never completely.

They would presumably up the cost to compensate and you would do the equivalent of taking out a mortgage to partake.
It still would. It's just that other pharma companies would be in the closet.