[misterkrabs]

There's also epigenetics to consider, like methylation and acetylation, which adds a whole extra layer of complexity. :/

[forgotmypw17]

I think it's really difficult not to underestimate the complexity, although software engineers have a unique perspective.

Have you ever maintained an application of vintage? You have some idea of how complex an application can get after a decade or two... Now, imagine an application which is X years old, where X is our age going back to the first ancestors...