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by dnautics
1916 days ago
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No mad cow disease is quite literally Creutzfeld-Jakob disease, it's vCJD, with v standing for "variant", to specifically distinguish it from "normal" CJD which is heritable. usually CJD is caused by a specific mutation in the human prion protein that renders its susceptible to turning into plaques; vCJD does not require this mutation and happens in wild type protein, though it's unclear if other heritable factors can contribute to susceptibility. (I worked in a protein plaque lab and did a small, inconclusive experiment about cross species CJD transfer) |
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"Classic CJD is not related to “mad cow” disease. Classic CJD also is distinct from “variant CJD“, another prion disease that is related to BSE."