Use the Lutris installer [1] and it will work great. It feels about as native as it gets, and it manages to hit 120 fps on my 1440p monitor with my meek 1050ti. Unbelievable performance, if you ask me. There's currently an issue where it will regenerate the shader cache with every launch, but it should only take 1-2 minutes with a decent CPU, which I normally spend in the training grounds. Once the cache is ready, performance is blistering fast.
[1] https://lutris.net/games/overwatch/