[Majromax]

> at what point do you budge?

Around the same time that you dispense with phase 3 trials entirely. It was more likely than not that the Pfizer/Moderna vaccines were effective by the time they'd completed phase 2 studies. If that is our standard, then we ought to have begun vaccinating at-risk individuals on a volunteer basis then -- in Fall of 2020.

To me, it's inconsistent to both say we need a full phase 3 clinical trial to grant authorization to a vaccine, but then to ignore the protocol of that phase 3 trial when distributing it.

[nojokes]

Alternative is to have a more detailed and parameterized protocol.

Regardless, the real solution should have been early human challenge trials and we would have had the vaccine already in the beginning of the summer most likely.