[cpeterso]

If you would like to develop cross-platform games, I would recommend checking out Ansca Mobile's "Corona", a Lua SDK for iOS and Android. Corona is mostly focused on game development, with libraries for things like animation, physics, and in-app purchases. The Lua is a popular scripting language in the commercial game industry (e.g. WoW extensions are written in Lua).

[coryl]

Unity3D seems to be a good engine, can port to web, android, iOS, XBox Live Arcade, Wii, etc.

I believe you can write in C#, Javascript, among other languages.