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> Do a search for the new devices promising blood pressure (Samsung I think) or blood glucose monitoring (Apple). One of those might fit your needs when they become available. Beyond that have a look at medical web sites to see what hospitals are using (although those devices tend to require a prescription and are usually only sold to hospitals).

This device is FDA approved to what you described (not blood glucose yet--but is technically capable): Biobeat Watch BB-613: https://www.bio-beat.com/copy-of-clinical-trials-and-researc...

It is Israeli technology and they do excel at things like photoplethysmography (PPG) and coulometry, from a historical standpoint.

But, the Empatica E4 is 100% capable of doing what you described above. You just have to use Lab Streaming Layer to interface with whatever you are programming in, such as Python. You basically reimplement prior research papers in your own code. However, it does not have an SpO2 sensor.