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by blakesterz
1955 days ago
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It'll be interesting to see how this theory stands up. It seems like they're on the right path, tying together several things that seem to be problems. The homeoviscous adaptation to dietary lipids (HADL) model explains controversies over saturated fat, cholesterol, and cardiovascular disease risk https://academic.oup.com/ajcn/article-abstract/113/2/277/610... "Corresponding with the model, we suggest alternative contributing factors to the association between elevated LDL cholesterol concentrations and ASCVD, involving dietary factors beyond SFAs, such as an increased endotoxin load from diet–gut microbiome interactions and subsequent chronic low-grade inflammation that interferes with fine-tuned signaling pathways." |
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