[PaulHoule]

A good question for many purposes is "Tell me about a problem that you solved?" which could be about something they did for for work or something they did for fun, the later one is better.

There are many variants of this open ended question ("hard problem", "was proud of", ... always some adjective or adverb that would be emotionally positive for an honest person) and most of the time the recipients feel a sense of relief and end up feeling pretty good about it. Often you find out a lot about what a person (did|does) (know|not know).

It's actually one of the most psychologically revealing questions that will catch the liar and professional bullshitter and leave them feeling like you dropped them 150 miles out at sea into the sharks -- and they deserve it.

I doubt that it works against the C-level psychopath because they know this question is coming so they hire a writer and take acting lessons.