Hacker News new | ask | show | jobs
by database_lost 1962 days ago
Would new shots adapted to novel strains have to pass the same trial process as the first versions of the vaccine? Or are there some provisions for an even faster approval? I don't know how it works for the flu vaccine.
2 comments

The flu vaccine skips the effective part of the trail, but still needs to go through safety tests for a few months.

I'm not sure at what point we are comfortable enough with vaccine technology to agree to that. There have been a few vaccine candidates in the past that made things worse, we think we understand the flu well enough to not worry about that. However for the new vaccines we don't have as much information.

Although if the virus keeps mutating there will be pressure to bypass the process to approve faster. That pressure is why the flu vaccine bypasses steps, if we did everything "by the book" we wouldn't have a working flu vaccine ever.

The FDA has announced that boosters to address novel strains will undergo a rapid review process. Full details of what that will involve are expected in 2 to 3 weeks.