[pinot]

For the large-scale tonnage using bioscience to create protein is incredibly capital, energy and water-intensive.

If you could do it anaerobically, that would help on the energy front, but there's big limit on volumetric efficiency (cell density/tankturn) of anaerobic.

For aerobics, maintaining lab-scale OTRs in 200m and larger reactors is very very power-intensive. kLa is a power-law relationship with power-input