Hacker News new | ask | show | jobs
by flobosg 1953 days ago
> What happens if a sub-sequence of peptide matches with one of our own's body proteins and our immune system starts building antibody against it?

The peptide sequences are listed on the whitepaper, so it’s a matter of BLASTing[1] them against the human proteome to check for possible matches. I just did it and there doesn’t seem to be any statistically significant hit.

[1]: https://blast.ncbi.nlm.nih.gov/Blast.cgi

1 comments

Ok great to know. But my intention here is to convey that it is dangerous to biohacking a molecule/compound that a user is going to put in his/her body. The peptides after synthesis needs to be rigorously tested(QC/QA) for the desired sequences and to make sure the absence of any undesired epiotopes mixed.
I agree on those points. That’s why I only focused on the cross-reactivity part of your post. Call it a nitpick, if you want.