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by beagle3 1960 days ago
The 95% everyone quotes is for mild disease.

For severe disease, Pfizer had 4 in the control group, and 1 in the vaccine group. That’s 75% RRR, with a confidence interval that spans 0-100%.

Look at the graphs here and in Pfizer’s. Immunity seems to taper at 12-18 days and stay there. The 2nd vaccine does not seem to confer more immunity - just expected to last longer time. This article looks at more severe disease than Pfizer’s 95% endloint (though possibly not severe as their “severe disease” endpoint - I don’t remember what definition each uses, but just in Israel the “severe” definition has changed several times)