I'm an average dude financially. Make less then 75k a year with a family of six. I could loose 50k in cash and be fine. My SO would be tiffed, but our life wouldn't change.
Somebody who doesn’t follow the markets probably wouldn’t, no. But those in /r/wallstreetbets aren’t unfamiliar with the machinations of the markets — for many of its core users, it’s not just some little side hobby.