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by knowaveragejoe
1976 days ago
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The next section in the article is what's important here: E484K mutation
The E484K amino acid change, a receptor-binding-domain (RBD) mutation, was reported to be "associated with escape from neutralising antibodies" which could adversely affect the efficacy of spike protein-dependent COVID vaccines.[50][51] The E484K spike mutation was linked to a case of reinfection with the 501.V2 variant of SARS-CoV-2 in Brazil, believed by researchers to be the first such case of reinfection involving this mutation.[29] The possibility of an alteration in antigenicity was referred to as an "escape mutation" from a monoclonal antibody with the capability of neutralising the spike protein variants of SARS-CoV-2.[52][53] |
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The links I posted show that testing with current mRNA vaccines against this exact variant are under way. Pfizer's (very small) initial tests results seem positive.