[theshadowknows]

Hi - as the person you replied to noted, you were a cancer researcher. I recently had a much beloved dog lose her fight with cancer (specifically, she had mass cell tumors that started on her leg and grew). All of her oncologists (we spent close to ten thousand dollars keeping her as healthy and happy for as long as we could) kept telling us that mass cell tumors in dogs are "very nasty" and pretty much told us on the outset that even amputating her leg probably wouldn't save her. So my question is, what about mass cell tumors makes them nasty and, as a follow up question, why is it that the tumors became resistant to each line of treatment that we used? We went through I think 6 different drugs until we ran out of options, and then kept her on prednisone for about a year to keep the growth slowed down until she started showing signs of declining.