[turminal]

I believe Alpine isn't meant to be used with pip, npm, and the like. Instead you are encouraged to create alpine packages out of your dependecies and submit them upstream. Writing a new package is completely trivial in Alpine, that's one of the things that made me switch to it.

[hn_acc_2]

Unfortunately the Python package ecosystem is enough of a headache.

Now we add additional complication "OK, these pip package authors have upstreamed Alpine packages, and these other ones are only on PyPi".

Maybe this approach would work if you can keep your Python dependencies to a small list of well-maintained packages

[nenolod]

The good news is that there is work in progress to untangle the mess with PyPI wheels and musl. But it is easy enough to just not use wheels.

[saagarjha]

They do work, though.