[pranavjoneja]

ASICs only make sense if you have high volume. PCI-e takes a lot of resources/space. The sweet spot for FPGA-CPU hybrid chips are embedded devices that are latency sensitive. For example, time-of-flight sensors and specialty cameras.

[dkersten]

I guess to overcome the reconfiguration latency others have mentioned, the use case would be systems that configure their custom instructions once on boot and then the software just sees a cpu as normal, just with these custom instructions. Ie not intended for reconfiguration on context switch.