[R0b0t1]

It is easy to purify small molecules with a filter. The filter could pose a problem to mRNA or DNA. But if everything in the injection is effectively dead the worst that will typically happen is a bad rash, though in some people the innate immune reaction could kill them.

[ramraj07]

I suppose you haven't heard of endotoxins yet

[R0b0t1]

Stop acting like God's gift to HN. I have. That is what causes the rash I mentioned. A test for endotoxin presence is sticking a pig and looking for a rash.

Pigs are hardy, but humans are too.

[ramraj07]

So pointing out you shouldn't go around injecting endotoxin laden crap into your body is now acting almighty is it? You sound like one of those biohackers who just injected live virus into his hands, good luck with your superpowers (or death) but keep it to your garage. People learned not to F with endotoxins a while back, apparently it's heresy to you to point that out.

[R0b0t1]

No, acting like you're the only one who knows what endotoxins is is acting almighty.

Besides that, the problem is overstating how much of an issue this actually is. For a medical product you need to cater to the long tail of humanity that might have a very adverse reaction to endotoxins. But most people, very nearly all of them, do not have such a reaction. People prepare their own IV drugs all the time. What kills them isn't a reaction to endotoxins (if there is any to react to in the first place, as it is quite easy to make chemically pure drugs) but side effects of the drug or infections from reusing injection equipment.

Mammals have been getting poked with sticks for millions of years.