That may be true. The lifestyle in Silicon Valley is pretty awesome. I've lived in and visited several world class cities and the Bay area outshines pretty much everyone. You might be able to increase your friend pool if you are a technical person. For example, MakerFaire is happening soon! Or you could go to Noisebridge in SF. I've had awesome random tech conversations with people at coffee places (MV used to be full of folks doing YC). The place has excellent weather (by my personal standards - I don't like rain and snow). You have Napa, Yosemite, Santa Cruz, Tahoe and a bunch of other places nearby for weekend getaways.
Other cities I can recommend: Vancouver and Dubai.
Vancouver is climatically bankrupt (exception: Apr - Oct, then its the most beautiful place, heaven on earth!). Costs are about half of what you're paying. I lived there for a decade and went to college there, let me know if you want to know more.
My point being the bay area is great to live regardless and you talk about your business doing great, you should be in silicon valley. (2 birds one stone.)
I know your just looking for locations, but your life is apart of business and your location is key. Why not improve both at the same time. :)
Other cities I can recommend: Vancouver and Dubai.