[twinge]

If you’ve flown a plane on autopilot, the experience is similar: you can direct your attention elsewhere and you end up less fatigued. You still need to be awake and alert but don’t have to worry about tedious things like holding a heading/drifting out of your lane or maintaining speed.

[tempestn]

I haven't flown myself, but I would guess when cruising in a plane, there's far less likelihood of hitting a stationary object should the autopilot mess up.

[ElFitz]

Yes. But sometimes, the plane randomly decides it should tenderly hug the ground.

See Boeing 737 Max and it’s infamous autopilot