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by tn890 1990 days ago
>Autoimmune reactions should happen in the short run, right?

I believe Pandermix took 6 months for narcolepsy to develop.
2 comments
learc83 1989 days ago
The important to thing to realize about Pandermix was that the rate of people impact was so small that even if we followed 50k phase 3 participants over 10 years, we wouldn't have uncovered the issue.

The narcolepsy issue was never going to be uncovered before it was rolled out large scale.

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toabi 1990 days ago
According to https://journals.plos.org/plosone/article?id=10.1371%2Fjourn...

the onset judged by "first contact to health care" was much earlier.

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flobosg 1990 days ago
There seems to be an early-onset but also long-standing effect, maybe due to circulating antibodies inducing the autoimmune response over time.
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zilian 1990 days ago
This does not make sense to me. Your own antibodies triggering an autoimmune response ?
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