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by djsumdog 2003 days ago
> All three of us developed SARS-CoV2 spike protein neutralizing antibodies. I still can't fucking believe it. Not only did we create and test a successful vaccine, we showed that we could get a gene therapy to work (a DNA vaccine changes the DNA in your cells and so is a gene therapy also)

Seems incredibly dangerous. What if 3 years from now, he realizes the changes he made are crashing his immune system? There is no "undo" button.
2 comments
gus_massa 2003 days ago
It changes the DNA in a few cells, that produce the spikes. These cells are killed by the white cells, and after a few steps you hopefully get immunity. The objective is no permanent change of your DNA.

(Actually from time to time a virus fail and it get copy to the DNA of the cells that produce sperms or eggs and it get copied in the next generations. We have a few of these virus, but it is not the usual outcome.)

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mam2 2003 days ago
I mean it's just a protein and a basic immune system response.
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