That's interesting that it's an N -> Y mutation, if it's a surface mutation, that AA shift is typically associated with tighter specificity in binding to it's target, e.g. and in antibody studies.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2829252/
https://nextstrain.org/groups/neherlab/ncov/S.N501?animate=2...