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by dnautics 2002 days ago
That's interesting that it's an N -> Y mutation, if it's a surface mutation, that AA shift is typically associated with tighter specificity in binding to it's target, e.g. and in antibody studies. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2829252/
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I think this is a NextStrain link to it. There's probably more information, jumping off from there.

https://nextstrain.org/groups/neherlab/ncov/S.N501?animate=2...