Voided as a term doesn’t make sense. The vaccine will be less effective for sure, correlated to the distribution of the variant vs. the original strain in the population.
It's not really clear how the vaccine and variant will interact. It can be the case that the vaccine confers strong immunity against the variant or that it doesn't confer any immunity at all, it's not necessarily predictable or linear.
That said, what I've seen immunologists saying is that they expect the vaccine to still work well, because they wouldn't expect months of mutations to add up to the variant escaping the vaccine.
That said, what I've seen immunologists saying is that they expect the vaccine to still work well, because they wouldn't expect months of mutations to add up to the variant escaping the vaccine.