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by wycy 2009 days ago
Do both vaccines require 2 doses? Also, is the second dose different or just a duplicate of the first?
1 comments

Both of the mRNA vaccines (Pfizer and Moderna) require two doses. Don't know if the 2nd dose is the same as the first.
Both the first and second doses of the mRNA vaccines are identical.
Could the first dose be one the Pfizer one and the second be the Moderna one? That might make logistics somewhat easier.
no. Might work, isn't tested.
Yep, my understanding is that the mRNA eventually degrade and disappear from your system, but your system requires more time to build enough antibodies.
The actual study results show the vaccine is highly effective within 10 days of the first dose.

Honestly a bit shocked based on the results and the number of lives that could be saved by effectively doubling the number of available doses that they didn’t try to get it modified to a single dose regimen.

Seems to me like just another way the FDA has screwed up this whole rollout.

Two doses is very common for vaccines because this is based upon how the immune system responds to real infections. The first dose will initiate a primary immune response. The second dose will act as a "challenge" to trigger a secondary immune response.
It sounds like one dose is enough to make you much less likely to develop serious symptoms or symptoms at all, and two doses gives you close to immunity.
Absolutely, after the first shot you do have immunity but it's not as fully developed compared with having two, so it will take longer to respond than with two, and that does present a larger window of opportunity for the virus to cause problems.