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by gus_massa
2020 days ago
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Did they synthetize the DNA in their kitchen, or they paid an specialized lab to do that part? > To date this is by far the largest dosage(10mg) of a DNA plasmid based gene therapy outside a clinical trial(all others have been in micrograms or single milligrams). Why? Is there any indication that a big dose is more effective? Luckily they had no big side effects, but any test of a candidate of a vaccine has a chance of a problem. That's why they are tested firs in very small groups and under medical supervision. A few days ago, the Pfizer vaccine caused a problem in two persons with an history of allergy problems. It is always a possibility. Also, there is https://en.wikipedia.org/wiki/Antibody-dependent_enhancement that has been observed in coronavirus. The clinical test for a vaccine are very important. |
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