[jskajakzkjx]

MDMA induces tolerance and requires dose escalation for redosing after the acute effects wear off. It’s like benzos, heroin, or speed in that respect. At least it will stop working eventually so few people would compulsively redose every day, but I’ve seen people who did it every weekend and eventually had a very bad time. Antidepressants, on the other hand, are designed for daily use (and generally require sustained use to be effective). The dynamic where you want more so you keep increasing your dose to fight tolerance until you end up worse than you started is less of a risk.

I don’t mean to attack MDMA. I think it’s great, and a lot of people could benefit from it. But I think this is a real issue if it’s easily available outside of a therapeutic context.

[loceng]

NAC (N-acetyl cysteine) supplement anecdotally reduces the tolerance that builds. Time passing also reduces the tolerance - I initially was told to not do MDMA more than every 4 months maximum.

[jason0597]

>I initially was told to not do MDMA more than every 4 months maximum.

Does that mean you are now doing it more frequently than every 4 months? If so, how often are you taking it?

[tonyhb]

NAC is also a must if you drink alcohol and appreciate your liver.