[sildur]

All mutations share the same spike protein, which the vaccine targets, and as far as we know the virus cannot reproduce without that exact same spike protein. Having the virus mutate in a totally different but still successful spike protein should be very very unlikely.

[SomeoneFromCA]

That is very strange claim. D614G is a mutation in the spike protein, and also there is a document ed case of very rapid mutation of the spike in an immuncompromised patient.

[mircea]

AFAIK the spike protein is used by the virus to gain entry into cells, it's not strictly related to reproduction. In theory the virus could mutate to gain entry into the cells via a different mechanism.