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by InclinedPlane 5533 days ago
Empty space isn't completely empty, even between galaxies. There are traces of gas, almost entirely Hydrogen, between galaxies. If there were entire galaxies made of anti-matter then the areas where their clouds of inter-galactic anti-gas contacted normal inter-galactic gas would be rife with emissions due to annihilations. The amount of matter should be enough to be detectable even at tremendous distances.