[LeifCarrotson]

For some, sure, if an API implements "new foo(), new foo(string), new foo(string, int), and new foo(string, int, int)" but the code that uses the library only uses "new foo()" and sets the other properties after creating the object then it would eliminate the extra constructors. Figuring out what stuff gets called is really hard in something as big as Chromium, where there are so many components that in some spots have their own domain-specific language to link stuff together.

For others, no, they do allow the minifier to break some sites: they analyze the Alexa top 1000 and check which functions get called and how often by those sites.