[Wintamute]

Coronaviruses like SARS-COV-2 mutate relatively slowly and minimally compared to others. So mutation isn't expected to be a huge concern, unlike say influenza which mutates relatively rapidly and requires an annual tweak to the vaccines.

What's more, any new strains we do see spreading more widely will do so because their mutations confer a competitive advantage. In practice that usually means more drift towards higher infectiousness but less severe symptoms - the same mechanisms that have left us with 4 other endemic but mild common cold coroanviruses.

The new SARS-COV-2 vaccines may be a useful tool to get us over this hump where the virus is still novel to a large proportion of the population, but are unlikely to be required indefinitely.

[bipson]

It was said (arguably in the news, so, nobody knows if true) that the mutation found in the mink populations in Denmark has a significantly different response to antibodies, in particular, they are less effective.

This is why OP is asking and mentioning the minks in Denmark.