Clojure is a big language, and pretty deeply tied to the JVM; I'm not sure how you'd put it on V8. Scheme is pretty practical, though, once you get used to it.
The first version of Clojure was a Common Lisp compiler that compiled Clojure down to JS to be run on Rhino. There's interest in the Clojure community to have a Clojure "Light" that runs on V8 or SpiderMonkey.