A mouse starves to death in 48 hours. I have gone 12 days without food (water fast) and was not even close to starvation. Probably could have gone another few weeks before I expired.
I would say 16 hours for a mouse is probably more like 7 plus days without food for a Human.
I started experimenting with fasting a about 2-3 years ago. My initial goal was weight loss (lost 100lbs from 272->172). My limit was typically 7 days but I wanted to see what the impact of a longer fast would do in the area of autophagy. I experienced some positive results but would discourage others from doing it, 3-5 days is more than enough. I would also discourage doing alternate day fasting or 24 hour fasting since it will screw up your metabolism (I ate 2 meals (2500kcal) every other day for 3 months) and found it very stressful on my general well being and metabolism.
These days I maintain 172 lbs with time delayed eating (18/6) and a clean diet.
Main goal for these kinds of fasts is weight loss, reducing insulin resistance and particularly extended fasts to achieve autophagy where your cells do internal house keeping to clean out broken cellular components and repair themselves.
My 5 -7 day water fasts helped with some minor skin issues and I have no joint pain anymore, but that might be from losing some serious weight. For every 1 pound of body weight you lose, I have heard it removes 4 lbs of pressure on the knee and lower back. My 12 plus day water fast cleared up any remaining skin blemishes and a little Vitiligo between my fingers disappeared. I'm thinking after a year of monthly 5-7 day water fasts (18/6 Time delayed eating the rest of the time), the 12 day water fast was incredibly impactful, it felt like my body was pushed to use anything it could at that point to fuel itself.
My only regret is that I wasn't able to have someone doing a study or researching fasting monitor and harvest the wealth of information that was available.
I would say 16 hours for a mouse is probably more like 7 plus days without food for a Human.