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by entitydc 2064 days ago
LSD isn’t still fully understood there, but from what I gather Psilocybin is probably a greater concern (more agonism on HT2B than LSD).

Neither show long term correlation with lower long term health outcomes (typically the reverse) but with microdosing being more prevalent and science being able to study more of this above ground, I’m hopeful we will have a better answer to this eventually.

https://www.reddit.com/r/DrugNerds/comments/2mqqww/psilocin_... - which has a ton of assumptions in it, but is very forthright with those, is one of the better analyses I’ve seen on this topic, but if there’s more out there I’d love to see it.

The gist that I’ve gathered so far is that for most people, going with a Fadiman-esque approach (2x/week dosing), combined with anecdotal data gathered from researchers conducting surveys, seems to suggest that it’s not egregiously unsafe, at the least. But still certainly worth paying attention to - a big part of the reason I cycle in and out of microdosing - it’s too helpful for depression, anxiety and disconnection to abandon completely, but there’s no such thing as a free lunch.