[DennisP]

The TAME trial is attempting to change that: https://www.afar.org/tame-trial

Another strategy is to apply an anti-aging drug to a specific disease of aging.

In any case, I guess I was really asking what these senolytic treatments are, and whether any of them are available now either as approved drugs or supplements.

[reasonattlm]

Dasatinib + quercetin has been shown in a clinical trial to remove senescent cells in humans in much the same way it does in mice [1].

High dose fisetin (i.e. take a whole bottle of the stuff at one go, not just a couple of pills) works about as well as dasatinib + quercetin in mice, but absent published results from the presently ongoing Mayo Clinic trial we're all dubious that will translate to humans, given how widely these sorts of compounds have been consumed, tested, and assayed [2].

Ditto piperlongumine.

Beyond that, there are any number of biotech startups developing senolytic immunotherapies, small molecules, gene therapies, topical cosmetics, etc. [3]

[1]: https://doi.org/10.1016/j.ebiom.2019.08.069

[2]: https://brain.forever-healthy.org/display/EN/Fisetin+Senolyt...

[3]: http://agingbiotech.info/companies/