[hexxiiiz]

This is huge. So much of what we seem to know about these neuromodulation systems amounts to a number of "has to do with ..."s. Dopamine has to do with reward; serotonin has to do with happiness; etc... Knowing how these modulators actually modulate in response to circumstances may give us a much better sense of what they are actually doing.

[padolsey]

Agreed! This'll be very insightful. I've always found the mainstream understanding of neurotransmission to be annoyingly one-dimensional. E.g. AFAIK dopamine is very ubiquitous within the brain, and has as much to do with reward as it does with motor function, so the way we only equate it with reward seems so limited. Seems we're slowly, but promisingly, moving beyond the age of "poking" the brain with random inhibitors and observing mere relations.