[netvarun]

On a somewhat relevant note - there was an interesting post I saw sometime back on designing an optimal keyboard layout https://news.ycombinator.com/item?id=21425426

[Aengeuad]

There's also Carpalx which is a parametric model rather than AI but in general goes into a lot of information on keyboard layouts in general.

http://mkweb.bcgsc.ca/carpalx/