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by Simon_says 2079 days ago
That platitude is not that helpful. What would Paracelsus' advice be on the toxic dose of vitamin B12?
3 comments

Not really sure your point. Are you saying that there is no upper safe limit for B12 for all people?

>...Case details: A young woman was treated with multiple daily doses of 1 mg of cyanocobalamin for severe pernicious anemia. After a total dose of 12 mg, she developed acne, palpitations, anxiety, akathisia, facial ruddiness, headache, and insomnia. She improved two weeks after stopping the drug. There were no sequelae nor complications.Discussion: Although these symptoms of cobalamin toxicity were unexpected and unusual, the case reminds us that the administration of any drug is not entirely safe.

https://pubmed.ncbi.nlm.nih.gov/31018715/

Vit B12 LXX kg fiat bolus sumendum ab alta oculus uterque hora somni ought to do the trick.

Determining LD50 is left as an exercise for the reader.

> That platitude is not that helpful.

And neither is a report simply saying it is possible to overdose on vitamin D.

Which was the point of the comment.