[samatman]

Agreed that it doesn't apply to microdosing, and single-blinding the scientists handling the data is valuable.

I don't think it's as important for the attending scientists, who are also going to have a pretty accurate guess. What's more important is that they have some training in 'trip sitting' and that the experimental environment be appropriately designed, DMT: the Spirit Molecule has a number of stories about how things go poorly when this aspect is neglected.