Interesting in the limelight of pandemics in regards to the closing paragraph:
> Today, H. sapiens doesn’t have the possibility of quickly grabbing a load of diversity by mating with another group: For perhaps the first time in our history, we’re the only humans on the planet. It’s another reason to miss our extinct cousins, says population geneticist Carina Schlebusch of Uppsala University. “To have such a large densely spread species with … so little genetic diversity … is a dangerous situation,” she says.
Even as the single human species we used to be spread into isolated groups, that's why different populations have specificities (e.g. skin colour, but also other adaptations).
Now that we have such a huge and interconnected population diversity will fade and adaptation will slow.
I don't think that genetic diversity will necessarily slow under those conditions. Genetic differences between people are already dominated by individual genetic differences over group genetic differences. Our diversity is more about us as individuals than as a collection of groups. Why, then, would the mixing of groups decrease diversity? I would think it would increase it.
For example, Tibetan people have developed a genetic adaptation to high altitude. This can only have happened because of the relative isolation of that specific population. Now that we are constantly mixing and have technology to fix everything such adaptations are much more unlikely to arise or even to be kept.
All in all, the global human population will become more homogeneous and less diverse.
I'm not so sure. Even with modern transportation technologies, the price of moving is still high enough that the number of single ethnicity births will generally outpace multi-ethnicity births. I don't think we have nearly enough airplanes and jet fuel to homogenize the genetics of ~8 billion people. But I also haven't run those numbers so feel free to change my mind.
Even if intercontinental interbreeding is still rare, societies and therefore breeding patterns have become far more connected on a local, national and intracontinental scale. Where there used to be the proverbial inbred populations in remote mountain valleys, mobility has completely erased the formation of such pockets. Same for marriages to other nationalities and religions. Where my german catholic grandmother might have gotten into trouble for marrying a protestant or a frenchman, nowadays that isn't a problem anymore.
Geographic variation will not dissappear completely, but the granularity and amplitude of those variations was and will continue to be smoothed a lot.
A few instances of "new blood" in a population can be enough because it will then spread over generations.
In many countries the proportion of foreign-born is >10%, so the mixing is quite intense in terms of evolutionary time scales.
If that continues for a few hundreds of years, diversity will have significantly reduced. Indeed, some suggest that e.g. skin colour may largely homogenise within a thousand years.
A thousand years might sound like a very long time wrt. a single individual's lifespan, but for these issues it is nothing at all. In addition, some traits (e.g. pale skin colour) are quite recent from what we know.
So Science Fiction Story time, immortal finds it difficult to blend into future less diverse population because their personal characteristics are no longer widely enough found that they can just wander off and go live somewhere else.
The last X is an easy target.
on edit: for anyone unfamiliar with this trope, see https://en.wikipedia.org/wiki/Requiem_for_Methuselah or https://en.wikipedia.org/wiki/The_Man_from_Earth (both written by Jerome Bixby, but many other examples by Neil Gaiman, etc. available) for easy clarification. One of the common ideas of the trope is that an immortal sooner or later becomes problematic to have in one place, they must wander of people will attempt to experiment on them to figure out the secret of immortality. Of course the second bit of the trope is the wandering immortal leave traces, and more intense searchers after immortality will follow them and attempt capture. If diversity decreases in the future based on present trends the story then becomes that it becomes increasingly difficult for the wandering immortal to wander without everyone being aware of them.
There are a number of other stories which address this as well.
Sometimes without the trope you mention (L. Sprague de Kamp's The Gnarly Man[0])
And sometimes with a variation on it (Heinlein's Methuselah's Children[1]), which he follows up with some of the same characters, but not invoking the trope (Time Enough for Love[2]).
There are many others of course, those are just the ones that came off the top of my head.
Whether or not all populations on Earth are mixing enough to prevent speciation remains to be seen. But the process begins with the kind of mutations documented in the article.
Are you advocating against interracial unions? On an argument that mixing leads to less diversity over time, thus implying that mating with those those most like ourselves is more genetically desirable? Ever heard of blue blood, or the Hapburgs?
This sentence doesn't make any sense: "H. sapiens doesn’t have the possibility of quickly grabbing a load of diversity by mating with another group".
It would make sense if she specifically referred to Homo sapiens sapiens, but for Homo sapiens that "other group" would be of a different species and we thus we shouldn't be able to produce fertile offspring with them.
Also Homo sapiens sapiens have plenty of genetic diversity. Even just the number of easily observable environmental adaptions present in populations are countless (Sherpa, Bajau people, etc.)
As for COVID-19, most people are more-or-less unaffected by it. Our genetic diversity is working as intended.
> but for Homo sapiens that "other group" would be of a different species and we thus we shouldn't be able to produce fertile offspring with them.
That's one definition of "species" (specifically, it's "the biological species concept"), but like all the other definitions, it doesn't work and does not correspond to most usage of the term. You can read modern genetic work discussing how homo sapiens interbred with hominids of other species. You can also observe how easily different species interbreed today, like wolves (canis lupus, obligatory pack animals) and coyotes (canis latrans, solitary).
It also wouldn't surprise me if "can reproduce with" isn't a transitive property (edit: actually, I'd be very surprised if it always is. genetic stuff is never that simple). So even if you try to collapse species into that strict definition, you'll still have edge cases that don't fit.
You don't even have to go as exotic as ring species. Climb up the evolutionary tree through each of your ancestors to some slime creature a billion years ago, and then climb down to your pet dog. Each connected node in that step can interbreed, but you can't mate with Fido.
> It also wouldn't surprise me if "can reproduce with" isn't a transitive property
"Can reproduce with" is not a transitive (or even a permanent!) property among individual humans. (For a more general transitivity allowing for the fact that it doesn't make sense to ask whether males can reproduce with males.)
>You can also observe how easily different species interbreed today, like wolves (canis lupus, obligatory pack animals) and coyotes (canis latrans, solitary).
Their taxonomy predates the more modern biological classification systems though. Things have been reclassified before and I expect they will be again.
[A bit of a rant:] Any classification system that can't tell you something about the objects it classifies is objectively useless for anything but naming things. You might as well use a random name generator, draw lines in the sand in geometrically pleasing ways, and pretend it's a "system".
> Any classification system that can't tell you something about the objects it classifies is objectively useless for anything but naming things
They are both canis, you know. The difference in species designation tells you very little because that's not a problem that can be solved. It's not an issue of misclassification. The specific designations latrans and lupus tell you a lot.
Canis is the genus. Even barring classification mistakes, cross-species breeding across genus is not impossible, it's just very less likely to produce viable and/or fertile offspring.
A classic example is the breeding between Equus Caballus (horse) and Equus Asinus (donkey): it works and you get a Mule.
The genetic difference between the horse and the donkey is non trivial, they even have a different number of chromosomes (64 vs 62). Since the offspring gets half of their chromosomes from the father and half from the mother, the mule gets an odd number of chromosomes (63) which clogs the gamete production machine and renders the animal sterile. (See https://genetics.thetech.org/ask/ask225).
Now, dogs and wolves don't have that problem. Does it mean they are same species and that the classification was applied to eagerly?
>Humans aren’t particularly genetically diverse, given our dispersal, though as far as I know there’s some disagreement on _why_.
That's absolutely correct. One set of hypotheses about this are population bottleneck theories[0].
As an example, the Toba Catastrophe Theory[1] posits that:
"The Youngest Toba eruption has been linked to a genetic bottleneck in human evolution about 70,000 years ago,[28][29] which may have resulted from a severe reduction in the size of the total human population due to the effects of the eruption on the global climate.[30] According to the genetic bottleneck theory, between 50,000 and 100,000 years ago, human populations sharply decreased to 3,000–10,000 surviving individuals.[31][32] It is supported by some genetic evidence suggesting that today's humans are descended from a very small population of between 1,000 and 10,000 breeding pairs that existed about 70,000 years ago.[33][34]"
Whether such theories are correct or not, they appear to fit with the lack of genetic diversity among humans.
I'd have assumed that it's largely because humans can spread to new niches via cultural evolution, which happens vastly faster than the old-fashioned biological kind. Much quicker to make a fur coat than evolve one.
You're overlooking the fact that even if easily breedable pool of foreign species existed along H. sapiens, given enough time they would either be purged or become common ancestors to everyone by now.
Since they were purged and exist as remnants in individuals' DNA.
If they are remanants in people's DNA, they did become common ancestors, no? Everyone's family tree collapses to the same individuals at 5500 BC, after the other humans went extinct.(1) That means we are all descended from non Homo Sapiens humans. What I'm trying to say is that they were not "purged," we are their descendants. We got most of our genetic material from the Homo Sapiens side, but there is continuity with the other species as well.
You don't necessarily have any DNA from any particular ancestor, but they would be your ancestor. This is explained in the article I linked. That means that if everybody's ancestors converged in 5500 BC, and at least one person had a Neanderthal as their ancestor, everyone has a Neanderthal ancestor.
Species is a much more fluid term than I think you realize.
Also, we don't know that most people are more or less unaffected by covid-19. We're only beginning to understand long term affects of even mild cases. Please don't spread misinformation.
My point wasn't to assume the worst, but to point out that we don't know what the long term affects of even mild cases are, and there is a non-trivial amount of mild-and-worse cases.
Covid is comparable to flu with a higher mortality rate. Don't make it bigger than it is. 99.95% of the people are doing perfectly fine. Genetics are thus pretty effective
Please, please, please stop saying that it is comparable to the flu in any way!
I got a mild case of COVID-19, even the doctors in the hospital agreed on that; I was able to help other patients do stuff they couldn't, I could easily climb 2 floor worth of stair while 90% of the patients had to make frequent resting stops.
37 days after first symptoms, I'm still not back to my previous energy levels, I still cough, I got tinnitus in my right ear and pain when ejaculating.
None of this has ever happened with any flu or cold that I ever got.
the 1918 spanish flu death rate was around 20%. It was only in March 2020 after covid19 was mainstream news it got edited in Wikipedia to show 2% (not sure if that's changed by now), you can check the edit history. But in short, in 1918, there were coffin shortages, compared to the toilet paper shortages with covid19.
covid19 and the Spanish flu are not even in the same weight class, not even a little bit, whereas yes, like it or not, covid19 is most likely in the same weight class as the flu depending on your thresholds with the flu at .1% and CV19 around .5 to 1% (likely closer to .5%).
yes, there are some people with long term effects of cv19. that's also true of the flu. Many scientists think age related dementia is caused by repeated exposures to the flu/cold. flu/cold have also caused heart and organ damage to many, it just doesn't get reported on. 'oh, this person died of organ failure, wonder why'. It's already a proven fact that the flu has caused the onset of type 1 diabetes for example. There are also many reported cases of heart disease caused by the flu. the flu sucks.
people loose their sh*t when you talk about this. it doesn't minimize the effect of covid19, it just highlights the flu is something serious. for some reason, people are too immature to handle that. or maybe it goes against their worldview we should burn the world to the ground in order to stop covid19.
So the definition of species being “can’t interbreed” is correct, but it doesn’t have to be a physical or biological inability to interbreed—-species can arise by being geographically separated, and merge into a new species if they eventually meet. In the same vein, two species can split from a single one if something happens to isolate a subset of a single species.
Man, I've always actually kinda wondered about this.
I know it's macabre, but I think about human migratory routines and when different groups clashed back when life was so primitive and brutish, they're must've been those tendencies to rape and sexually conquer the opposition.
Surely that is reflected in the genetic ledger of time. What a crazy insight. Genetics is such an interesting field. It's bonkers there's just strings of data that we can read the past through.
I encourage you to explore the early history of the pre-Roman Empire peoples. These were largely mythologies that the romans retroactively constructed for themselves (i.e. they had the opportunity to omit the raping and kidnapping in retellings, but chose not to).
It’s full of “and then tribe X invaded and the land of Y, took their women and enslaved their men”. Back and forth for centuries. This behavior was cyclical, inevitable, and universal, until violence was monopolized and institutionalized.
We’ve come a long way, I guess. Still have work to do.
I think GP was thinking about early humans, back when other species of humans still existed.
From what I understand, the most common view is that in hunter-gatherer times there was much less inter-group violence than there was after the advent of agriculture, simply because there was much less of a notion of territory and any need to defend it before agriculture was a thing.
"Only in the cities of these peoples that the LORD your God is giving you as an inheritance, you shall not leave alive anything that breathes. But you shall utterly destroy them, the Hittite and the Amorite, the Canaanite and the Perizzite, the Hivite and the Jebusite, as the LORD your God has commanded you,...? Deut. 20:16..
There was inevitably conflict, but I'm skeptical of the "tendencies to rape and sexually conquer the opposition" framing. AFAIK there isn't much evidence for large amounts of inter-group violence. A paper like https://onlinelibrary.wiley.com/doi/full/10.1002/ajpa.23751 lays out a contra case that the absence of evidence isn't evidence of absence--but I think it is a reason to be cautious about what we project back on those populations.
Oh well I mean sure, there's a similar case with colonists and slaves too, right?
I think at some point in the far past though there might have been a wider gap, genetically, between the two forces meeting. I haven't had time to read the whole article in detail, just skimmed it.
Anyhow, thanks. You're right, there's definitely been plenty of mandatory diversification before.
What would the 'first' of a species be, in an objective sense? As I understand it, speciation is a gradual process. Trying to pin down exactly where the change occurs is like trying to pin down precisely where a rainbow gradient shifts from green to yellow. You can pick a point and declare that to be the demarcation line, but discrete categorization in this way seems inherently arbitrary.
Even seeming straight forward metrics like "can they produce viable offspring" isn't so black and white, since between 'yes' and 'no' exists a continuum of 'maybe's. In very rare cases even horses and donkeys can have fertile offspring, e.g. mules that aren't mules (the typical infertility of mules has lead to the occasional use of the term to describe any infertile hybrid.)
It's a running joke in Dr who, where as humanity spreads into the starts there eventually ceases to be any pure humans (and many other alien species) because humans will mate with anything.
I think it's most interesting to think of how fluid what we mean by species really is. We've always known it was fluid, but I think many people never really consider that when thinking about ourselves.
For Star Trek, in-universe this happened at least twice. The relevant episodes are TOS 2x22 Return to Tomorrow [0] and TNG 6x20 The Chase [1].
VOY 3x23 Distant Origin [2] also in-universe establishes convergent evolution is very likely to create humanoids (makes no reference to the other two episodes, as far as I remember, but it's kinda wishy-washy in that it could be highly likely because of the two progenitor species).
That said, there's plenty of non-humanoid aliens. Off the top of my head: Q, the Tholians, the Caretaker's species, the two aliens from TOS 2x01 Catspaw (shown to be tiny and kinda birdlike in the final scenes), and Species 8472.
Oh, I was referring to progenitor seeding specifically. In terms of interbreeding, there's a few more prominent ones: Spock, B'Elanna Torres, and Alexander Rozhenko and B'Elanna's daughter (who are respectively 3/4 human and 1/4 human, showing there likely isn't an infertility problem like with mules [0]).
(Though I admit that the ENT example was certainly unique in the differing biologies)
Of the two relevant episodes in my other comment ( https://news.ycombinator.com/item?id=24726335 ), the TOS one explicitly states that that seeding doesn't apply to Earth because of the fossil record and when it occurred (but could explain some of Vulcan's history), while the other one was so early on that Earth was still in the primordial-soup stage.
Dr. Who is wrong. We could not mate with anything amongst the stars. Even if aliens exist they would be radically different. You might as well as bone your VCR.
The act of separation would create new species. Not our drive to bone.
Given that we have absolutely no idea what other biological systems could look like, what you're saying seems extremely likely, but not an absolute certainty.
It's near certainty. I mean it's not absolutely certain that your nearest pencil won't transform into Jesus and tell you the message that will unite all of humanity. I kinda doubt you would entertain it though.
> The story of human evolution is full of ancient trysts. Genes from fossils have shown that the ancestors of many living people mated with Neanderthals and with Denisovans, a mysterious group of extinct humans who lived in Asia
In the case of Neanderthals, isn't that "all" people rather than "many" people?
Neanderthals are believed to have gone extinct 40000 years ago.
But there was an article here the other day about the genetic isopoint [1], which is the most recent time when every human alive then was either an ancestor of every human currently alive or had no descendants that are currently alive.
Most researchers put the genetic isopoint somewhere between about 4000-15000 years ago.
If both of these are true (or even if not, as long as the genetic isopoint is after Neanderthal extinction), then all my ancestors that descended from Neanderthals and were alive at the genetic isopoint are also your ancestors, and so you are also descended from Neanderthals through them.
There seems to be a lot more uncertainty about when the Denisovans went extinct. It seems likely that they were probably also all gone by the isopoint and so "all" rather than "many" probably goes for them too.
Your kids only get half your DNA, their kids only get half their DNA, and so on. You can eventually end up with descendants who have none of your DNA.
If the genetic isopoint really was after the Neanderthals went extinct than everyone in sub Saharan Africa has Neanderthal ancestry even if none of them have Neanderthal admixture.
I'm not sure it's 'all'. Khoi-San peoples were pretty well isolated reproductively until recently and diverged before the Neanderthal introgression dates that I'm aware of. They're pretty much the reason the mt-MRCA and Y-MRCA dates are so old.
The paper Neanderthal-Denisovan ancestors interbred with a distantly related hominin [1] suggests a simple model of hominid population movement
> ...which involves only three expansions of humans from Africa into Eurasia: an expansion of early Homo at about 1.9 Ma ago, an expansion of neandersovans at about 700 ka ago, and an expansion of modern humans at about 50 ka ago.
The “early Homo” or “superarchaics” are H. erectus and their DNA contribution is inferred since no sequences have yet been extracted. “Neandersovans” is the common ancestor of European Neanderthals and Asian Denisovans.
Interbreeding occurred in Eurasia after the second and third expansion.
> Today, H. sapiens doesn’t have the possibility of quickly grabbing a load of diversity by mating with another group: For perhaps the first time in our history, we’re the only humans on the planet. It’s another reason to miss our extinct cousins, says population geneticist Carina Schlebusch of Uppsala University. “To have such a large densely spread species with … so little genetic diversity … is a dangerous situation,” she says.