[neuronic]

> brute-force trial and error

That's just another nice way to describe evolution. It's just a storm of probabilistic biochemistry. I think if you read about how fast and crowded biochemical interactions in the cell are [1], you will quickly appreciate that's it's basically just quadrillions of hypersonic processes doing what you describe as "brute-force trial and error".

For example, that's how a good number of drugs work that attempt to bind to some protein, like Aspirin. They don't go and find it. The drug molecules enter the cell space and just bang around at incredible speeds until they finally just jam into the protein they need to. Brownian motion and similar effects and not some taxi service to the target protein. It's basically just probability which is where concentration comes from. Increasing the probably of the drug molecule hitting the target.

That's also why I really dislike the personification of things. SARS-CoV-2 didn't consciously do anything. I know most people know, but the language constantly insinuates just that.

[1] http://www.righto.com/2011/07/cells-are-very-fast-and-crowde...