Except then spammers who send to [huge list of words]@your-domain.com all go to your inbox. It's much safer to use a regex pattern or generate forwarding emails ad hoc.
Please contact me at f7m4 {at} proxyto.me if you have any interest in beta-testing an app that does this exact thing.
Yep, I've been doing this for nearly a decade. This in combination with Gmail's spam filter works just fine. I have caught quite a few emails to my parents from people who can't spell their (simple) email address.