[dalbasal]

Possibly responsible for many of the reported differences between dmt (especially traditional oral varieties such as ayahuasca) and lsd or psilocybin. The latter are often used in recreational (and often irresponsible) settings, while dmt is often treated more seriously.

Even in a controlled test, expectations probably still play a meaningful role. Possible ethical issues with randomizing the active test.

[non-entity]

That's a good point as well, but I wonder if this will change over time as DMT seems to become more known and talked about.