[volkse]

The russian vaccine is also based on adenovirus vectors. Not clear if the method of delivery is to be blamed here, but it could be the cause for the adverse effects..

[YarickR2]

They (russians) are conducting large scale phase 3 experiment, with up to 40k volunteers. Need to watch closely; most of the volunteers are in Moscow, and it will be difficult to conceal high rate of side effects .

[kurthr]

Careful, because a "high rate" would be ~1/100k. Even a two SAEs in that cohort size, would be a huge deal and enough to shut down most efforts.

Edit: also note that the Russian Gamaleya vaccine is actually 2 vaccines one with a human adeno virus carrier and the other with a (chimp?) Ad5 and Ad26. So you could have a response to either one of them, or both. The problem with using a human viral carrier is that pre-exposed might fight it off without developing nCoV immunity.

[tinus_hn]

Pretty dumb because the damage from the real virus, both the damage from the illness and from the measures against it, is much worse than that.

[ck2]

can't find the link at the moment but there is now some academic comment that the russian data has some fakeness to it