[nradov]

No one will be told to go intentionally infect themselves. There will be no human virus challenge trials in the US as that would obviously never pass a review board. Instead they will vaccinate a study group and then compare infections, symptoms, and deaths versus a control group.

The best estimate of infection fatality rate is 0.65%, not 1%.

https://www.cdc.gov/coronavirus/2019-ncov/hcp/planning-scena...

[orwin]

I think this is the right IFR for the US, maybe a confidence interval is necessary however. In early April, data scientists paid by ARSGE calculated the IFR in france based on the diamond princess and found .7%, +- .2%, and estimated the high early IFR in spain and Italy was due to missing asymptomatic people and mismanagement. This pdf should still be available.

US having a relatively younger population, .65% seems correct.