[Reelin]

Lacking in raw physical power by comparison, sure. But what health issues do we avoid? Do new health issues arise? Optimality in a complex environment is inevitably a nontrivial trade off; we aren't forced to hunt animals with primitive weapons or contend with widespread famine in the modern world.

[mr_toad]

> But what health issues do we avoid?

Infant and child mortality is much much lower.