[otterlicious]

I learned from this guide (well the PyQt4 version). It starts off small and works up to the kitchen sink if that's what you need:

http://zetcode.com/gui/pyqt5/

There are a few others here:

https://wiki.python.org/moin/PyQt/Tutorials

The 2020 one there may be what you're looking for, more than hello world but doesn't quite all the way get to the kitchen sink, just maybe the silverware drawer.