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by jashephe
2130 days ago
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Just to clarify — the vaccine uses as its backbone a type of adenovirus that typically infects chimpanzees, modified by the addition of pieces from SARS-CoV-2, but the experiments testing efficacy are performed in mice (specifically, a type of mice engineered to express humanized ACE2). This vaccine has not been tested in chimpanzees (and actually such experiments would probably be a challenge, since they may have existing immunity to the backbone adenovirus). (edit: parent comment initially mentioned experiments in chimpanzees rather than mice) |
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